depends on what kinda sound you want to get out of it
the humbuckers will give you a totally differnt sound then the single coils
fender has tremolo, gibson doesnt
gibson is a thru-neck, fender is a bolt on
the only thing similar to each other is that they are electric
my suggestion is to figure out what kinda stuff you wanna play on it then from there you will be able to determine what one is best for you