I think after VR Slash would be open to working with Gn'r again but Axl marching on as Gn'R kind of ruins that. Axl should have the balls to go out as a new band and if Gn'R ever worked together it would be great, and if they didn't then legacy wouldn't be tarnished anymore than it is being now.
Axl should have the balls to be a man. He needs to learn to take care of himself, rather than relying on crazy people around him and making excuses like "it wouldn't be healthy for me".
If Axl can't learn to be a man and take care of himself, then his life is always going to be just the way it is now. Some rich guy in a mansion working on his precious album, living with his "mother".